Is Mounjaro the Same as Ozempic?

At Elite Primary Care Group, we are committed to providing our patients with the most effective and up-to-date treatment options for managing type 2 diabetes and supporting healthy weight loss. Two injectable medications that have been shown to help with both blood sugar control and weight loss are Mounjaro (tirzepatide) and Ozempic (semaglutide GLP-1). While both are valuable tools in weight management, there are important differences between them.

Ozempic contains semaglutide, a GLP-1 (glucagon-like peptide-1) receptor agonist. This medication works by helping to regulate your blood sugar and by reducing appetite, which can lead to weight loss for many patients. Mounjaro contains tirzepatide, which is unique because it targets two hormone pathways—GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors. By influencing both pathways, Mounjaro may provide additional benefits for blood sugar management and appetite control compared to GLP-1 agonists alone.

Clinical studies have shown that both medications can result in significant weight loss for individuals with type 2 diabetes. Recent head-to-head studies suggest that Mounjaro may offer even greater average weight loss compared to Ozempic at higher doses.

For example, patients taking tirzepatide have seen average weight reductions of up to 22.5% of their body weight, while those on semaglutide (at the weight management dose) have averaged around 15% weight loss. Of course, individual results vary, and factors such as lifestyle, diet, and any other health conditions will play a role. At Elite Primary Care Group, our experienced providers will work closely with you to determine which medication may be best suited to your unique health needs and goals.

At Elite Primary Care Group, we are committed to offering the most advanced and effective treatment options for supporting weight loss. Two injectable medications that have shown great promise in these areas are Mounjaro and Ozempic.

• Ozempic: Ozempic is a GLP-1 receptor agonist, meaning it mimics the effects of the natural hormone GLP-1. GLP-1 helps regulate blood sugar by stimulating insulin release, suppressing glucagon (which raises blood sugar), and slowing gastric emptying. These actions not only improve blood sugar control in patients with diabetes but also help reduce appetite, which can contribute to healthy weight loss.

• Mounjaro: Mounjaro, on the other hand, takes a more comprehensive approach. As a dual agonist, it targets both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors. The GIP receptor plays an important role in regulating insulin and appetite, providing an additional mechanism for improved blood sugar control and appetite suppression. Clinical studies have shown that Mounjaro can lead to even greater improvements in blood sugar control and weight loss compared to medications like Ozempic, which only target the GLP-1 receptor.

At Elite Primary Care Group, we understand that every patient is unique. While both Mounjaro and Ozempic are highly effective options for supporting weight loss, individual responses may vary. The best choice for you will depend on your health history, goals, and personal preferences. Our experienced providers will work closely with you to determine which medication is most suitable for your needs and develop a personalized treatment plan that ensures ongoing support and monitoring.

At Elite Primary Care Group, we are committed to offering the latest evidence-based options to support healthy weight loss. Two advanced injectable medications—Mounjaro and Ozempic— have shown significant benefits for both blood sugar control and weight management.

Here’s a comparison between the two medications:

• Mounjaro’s Dual Action: Mounjaro is unique as a dual agonist, targeting both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. This combined action may enhance its ability to promote fat loss and improve overall weight reduction compared to medications that target only one receptor.

• Ozempic’s Focus on GLP-1: Ozempic, on the other hand, works specifically as a GLP-1 receptor agonist. While it is highly effective for weight loss and blood sugar control, its impact on fat loss may be somewhat less pronounced than Mounjaro’s due to its more targeted mechanism.

• Comparative Results: Clinical studies, such as the SURPASS and SURMOUNT programs, have indicated that Mounjaro may lead to greater fat loss than Ozempic. In these studies, participants taking Mounjaro experienced average weight losses of 15% to over 20% of their body weight at higher doses, with the majority of this weight loss coming from fat. Meanwhile, participants using Ozempic typically saw weight reductions of about 10–15%, with a similar proportion of fat loss.

At Elite Primary Care Group, our providers use these findings to create personalized treatment plans. We understand that individual results can vary based on dosage, adherence to treatment, diet, exercise, and starting weight. Our team will work closely with you to determine whether Mounjaro, Ozempic, or another option is the best choice for your specific health goals, whether you’re focused on sustainable fat loss. We’re here to support you on your journey to better health.

At Elite Primary Care Group, we are committed to offering the latest, evidence-based solutions to help our patients achieve their health and wellness goals. One such option is Mounjaro (tirzepatide), a once-weekly injectable medication that was originally approved for type 2 diabetes and is now FDA-approved for weight management in adults with obesity or overweight and at least one weight-related health condition.

Here’s how Mounjaro works and what it can do for patients with obesity but no diabetes:

Dual Hormonal Action: Mounjaro mimics two natural hormones—GLP-1 and GIP—that play key roles in regulating blood sugar and appetite. By targeting these pathways, Mounjaro helps reduce hunger, curb cravings, and improve metabolic health.

Proven Weight Loss: Clinical studies, including the SURMOUNT-1 trial, have shown that Mounjaro can help people with obesity (without diabetes) lose an average of 15% to over 20% of their body weight. This makes it a promising option for those seeking significant and sustained weight loss.

Outperforms Other Medications: In some studies, Mounjaro has even outperformed other injectable medications like semaglutide (Wegovy), showcasing its potential for effective weight management.

While Mounjaro has demonstrated impressive results, it’s not suitable for everyone. Some common side effects include nausea, vomiting, diarrhea, and constipation, especially when starting or increasing the dose. Additionally, it may not be recommended for individuals with a history of certain medical conditions, such as thyroid cancer or pancreatitis.

At Elite Primary Care Group, our experienced providers take a personalized approach to weight management. We’ll work closely with you to assess your medical history, discuss your weight loss goals, review potential side effects, and determine if Mounjaro is the right fit for you. We also emphasize a comprehensive approach to weight management, combining medication with nutrition, exercise, and behavioral support to maximize long-term success. Let us help you develop a safe, effective, and individualized plan for better health.

At Elite Primary Care Group, Dr. Fahima Azizi and Dr. Rita Kapoor consider both Mounjaro (tirzepatide) and Ozempic (semaglutide GLP-1) as effective treatments for weight loss and blood sugar control, but they are aware of key differences. Ozempic works by activating the GLP-1 pathway, which helps reduce appetite and slow stomach emptying. However, Mounjaro targets both GLP-1 and GIP receptors, making it a dual-action medication that may offer greater appetite suppression and improved metabolism for some patients.

In clinical studies, Mounjaro has been shown to produce more significant weight loss than Ozempic. Dr. Azizi and Dr. Kapoor carefully assess each patient’s unique health profile, including their response to previous treatments, to determine whether Mounjaro might be more effective for weight loss and metabolic health. They work closely with patients to ensure the chosen treatment aligns with their goals and overall health needs.

For more information, contact us or schedule an appointment online. We are conveniently located at 801 Toll House Avenue, Suite E1, Frederick MD 21701. We serve patients from Frederick MD, Mt Pleasant MD, Braddock Heights MD, Walkersville MD, Lewistown MD, Urbana MD, Ballenger Creek MD, and surrounding areas.